Drug-Membrane Interactions Studied in Phospholipid Monolayers Adsorbed on Nonporous Alkylated Microspheres

Indirect interactions of membrane-adsorbed cylinders.

Biological and biomimetic membranes often contain aggregates of embedded or adsorbed macromolecules. In this paper, the indirect interactions of cylindrical objects adhering to a planar membrane are considered theoretically. The adhesion of the cylinders causes a local perturbation of the equilibrium membrane shape, which leads to membrane-mediated interactions. For a planar membrane under late...

Phospholipid Monolayers

Peptide-membrane interactions studied by a new phospholipid/polydiacetylene colorimetric vesicle assay.

Interactions between peptides and lipid membranes play major roles in numerous physiological processes, such as signaling, cytolysis, formation of ion channels, and cellular recognition. We describe a new colorimetric technique for studying peptide-membrane interactions. The new assay is based on supramolecular assemblies composed of phospholipids embedded in a matrix of polydiacetylene (PDA) m...

Phonons and librons in nitrogen monolayers adsorbed on graphite.

Phase Transitions in Phospholipid Monolayers Studied by Atomic Force Microscopy and Langmuir-Blodgett Technique

The phase behaviour and surface structure of dipalmitoyl phosphatidyl choline (DPPC) monolayers at the air/water interface, in the absence and the presence of procaine, have been investigated by LangmuirBlodgett (LB) technique and atomic force microscopy. The LB films were transferred on mica, at a controlled surface pressure, characteristic for the expanded liquid to condensed liquid phase tra...